| Date | Location | Result | |
| Apr 24, 2021 | St. Charles, MO | Lindenwood 18, Lewis 4 | Box score |
| Apr 22, 2021 | Romeoville, IL | McKendree 16, Lewis 9 | Box score |
| Apr 18, 2021 | Romeoville, IL | Lewis 12, Maryville (MO) 8 | Box score |
| Apr 16, 2021 | Romeoville, IL | Lewis 14, Quincy 5 | Box score |
| Apr 11, 2021 | St. Joseph, MO | Missouri Western 15, Lewis 13 | Box score |
| Apr 09, 2021 | Kansas City, MO | Rockhurst 19, Lewis 1 | Box score |
| Apr 07, 2021 | Pepper Pike, Ohio | Lewis 18, Ursuline 4 | Box score |
| Apr 03, 2021 | Indianapolis, IN | Indianapolis 25, Lewis 1 | Box score |
| Mar 14, 2021 | Cleveland, Tenn. | Lee 15, Lewis 10 | Box score |
| Mar 13, 2021 | Cleveland, TN | Alabama Huntsville 16, Lewis 7 | Box score |
| Feb 28, 2021 | Romeoville, IL | Lewis 16, CARROLL 6 | Box score |
| Feb 21, 2021 | Romeoville, IL | Concordia-St. Paul 13, Lewis 3 | Box score |