| Date | Location | Result | |
| Apr 29, 2022 | Indianapolis, IN | Indianapolis 16, LEWIS 11 | Box score |
| Apr 23, 2022 | Romeoville, IL | LEWIS 13, Maryville (Mo.) 9 | Box score |
| Apr 16, 2022 | Quincy, IL | LEWIS 10, Quincy 2 | Box score |
| Apr 09, 2022 | St. Charles, MO | Lindenwood 14, LEWIS 10 | Box score |
| Apr 02, 2022 | Romeoville, IL | Rockhurst 15, LEWIS 10 | Box score |
| Mar 26, 2022 | Romeoville, IL | LEWIS 11, WALSH 6 | Box score |
| Mar 23, 2022 | Indianapolis, IN | Indianapolis 10, LEWIS 6 | Box score |
| Mar 15, 2022 | St. Louis, MO | LEWIS 14, Alabama Huntsville 12 | Box score |
| Mar 13, 2022 | St. Louis, MO | LEWIS 15, Embry-Riddle (FL) 10 | Box score |
| Mar 09, 2022 | Romeoville, IL | LEWIS 12, Davenport 3 | Box score |
| Mar 05, 2022 | Painesville, Ohio | Lake Erie 13, LEWIS 9 | Box score |
| Feb 26, 2022 | St. Louis, MO | LEWIS 15, Maryville (Mo.) 13 | Box score |
| Feb 21, 2022 | Erie, PA | Mercyhurst 17, LEWIS 5 | Box score |
| Feb 12, 2022 | Romeoville, IL | LEWIS 18, Wheeling 6 | Box score |
| Feb 06, 2022 | Greensburg, PA | LEWIS 14, Seton Hill 13 | Box score |