| Date | Location | Result | |
| Apr 17, 2021 | East Peoria, IL | Missouri S&T 3, LEWIS 1 (25-18,25-21,19-25,25-18) | Box score |
| Apr 16, 2021 | East Peoria, IL | LEWIS 3, Truman 0 (25-11,25-22,25-22) | Box score |
| Apr 10, 2021 | Romeoville, IL | Southern Ind. 3, LEWIS 2 (21-25,24-26,25-18,25-21,15-8) | Box score |
| Apr 09, 2021 | Romeoville, IL | LEWIS 3, UIndy 0 (25-19,25-20,28-26) | Box score |
| Apr 02, 2021 | Lebanon, IL | LEWIS 3, McKendree 0 (25-18,25-19,25-21) | Box score |
| Mar 27, 2021 | Romeoville, IL | LEWIS 3, Ill. Springfield 0 (25-16,25-20,25-13) | Box score |
| Mar 20, 2021 | St. Louis, MO | LEWIS 3, Missouri S&T 2 (25-21,17-25,21-25,26-24,15-10) | Box score |
| Mar 20, 2021 | St. Louis, MO | LEWIS 3, Maryville (MO) 1 (25-10,25-18,15-25,25-16) | Box score |
| Mar 13, 2021 | Romeoville, IL | LEWIS 3, Lindenwood (MO) 0 (25-23,25-18,25-22) | Box score |
| Mar 13, 2021 | Romeoville, IL | LEWIS 3, William Jewell 0 (25-20,25-22,25-22) | Box score |
| Mar 6, 2021 | Kansas City, MO | LEWIS 3, Quincy 0 (25-22,25-19,25-20) | Box score |
| Mar 6, 2021 | Kansas City, MO | LEWIS 3, Rockhurst 1 (25-23,25-12,17-25,25-14) | Box score |
| 02/28/21 | Kirksville, MO | LEWIS 3, Drury 0 (25-15,25-12,25-18) | Box score |
| 02/28/21 | Kirksville, MO | LEWIS 3, Truman 0 (25-17,25-17,25-18) | Box score |
| 02/20/21 | Romeoville, IL | LEWIS 3, Mo.-St. Louis 0 (25-17,25-11,25-22) | Box score |
| 02/12/21 | Springfield, IL | LEWIS 3, Ill. Springfield 2 (25-16,28-30,25-16,22-25,15-9) | Box score |
| 02/06/21 | Romeoville, IL | LEWIS 3, McKendree 0 (25-18,25-15,25-19) | Box score |
| 01/30/21 | Indianapolis, IN | LEWIS 3, UIndy 0 (25-16,25-14,26-24) | Box score |
| 01/29/21 | Evansville, IN | LEWIS 3, Southern Ind. 2 (22-25,25-22,23-25,25-22,15-6) | Box score |