| Date | Location | Result | |
| Nov 20, 2021 | Painesville, OH | Lake Erie 2, LEWIS 1 | Box score |
| Nov 18, 2021 | Painesville, OH | LEWIS 2, Davenport 0 | Box score |
| Nov 7, 2021 | Romeoville, IL | Drury 1, LEWIS 0 (2OT) | Box score |
| Oct 31, 2021 | Rolla, MO | LEWIS 3, Missouri S&T 0 | Box score |
| Oct 29, 2021 | St. Louis, MO | LEWIS 2, Maryville (MO) 1 | Box score |
| Oct 24, 2021 | Romeoville, IL | LEWIS 2, Southwest Baptist 0 | Box score |
| Oct 22, 2021 | Romeoville, IL | Drury 0, LEWIS 0 (2OT) | Box score |
| Oct 17, 2021 | Liberty, MO | LEWIS 4, William Jewell 1 | Box score |
| Oct 15, 2021 | Kansas City, MO | LEWIS 2, Rockhurst 1 | Box score |
| Oct 10, 2021 | Romeoville, IL | LEWIS 2, Quincy 0 | Box score |
| Oct 8, 2021 | Romeoville, IL | LEWIS 1, Truman 0 | Box score |
| Oct 1, 2021 | Springfield, IL | Illinois Springfield 2, LEWIS 1 | Box score |
| Sep 26, 2021 | Evansville, IN | Southern Indiana 2, LEWIS 1 | Box score |
| Sep 24, 2021 | Indianapolis, IN | LEWIS 1, Indianapolis 1 (2OT) | Box score |
| Sep 19, 2021 | Romeoville, IL | Mo.-St. Louis 2, LEWIS 1 (2OT) | Box score |
| Sep 17, 2021 | Romeoville, IL | LEWIS 2, McKendree 1 (2OT) | Box score |
| Sep 12, 2021 | Romeoville, IL | Lewis 4, Lindenwood (MO) 1 | Box score |
| Sep 09, 2021 | Romeoville, IL | LEWIS 2, Northern Mich. 0 | Box score |
| Sep 05, 2021 | Romeoville, IL | Parkside 3, Lewis 3 (2OT) | Box score |
| Sep 02, 2021 | Hammond, IN | LEWIS 3, Purdue Northwest 2 | Box score |